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DISCLAIMER: This prank is intended for personal use on those overly sensitive persons with low self-esteem, no sense of humor, and bowel issues. These pranks are unsuitable for victims with weak hearts, small bladders, queasy stomachs and expecting mothers. Prankked.com can not be held responsible for your victims reactions or damage / injury that may or may not happen to yourself or property.
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If you have the time and the victim is away, you can use a blender to grind the Alkaseltzer.
To up the irony level….
Use a coffee grinder to grind up the Seltzers